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Exforge 10/160, For High Blood Pressure – 28 tab

74.00 SAR

Exforge 10/160 tablets are a combination medication containing Amlodipine 10 mg and Valsartan 160 mg. It is used to treat high blood pressure (hypertension) in adult patients when single-drug therapy with Amlodipine or Valsartan is inadequate. Amlodipine relaxes blood vessels, and Valsartan blocks a substance causing vasoconstriction, leading to reduced blood pressure and improved cardiovascular health


Amlodipine 10 mg + Valsartan 160 mg is a combination medication sold under the brand name Exforge 10/160 tablets. It falls under the category of anti-hypertensive drugs, which are used to treat high blood pressure (hypertension) in adult patients when monotherapy with either amlodipine or valsartan alone is not sufficient.

Mechanism of Action:

  • Valsartan is an angiotensin II receptor blocker (ARB), which means it blocks a substance in the body that causes blood vessels to constrict. This action results in the relaxation of blood vessels, leading to lower blood pressure and increased blood and oxygen supply to the heart.
  • Amlodipine inhibits calcium ion influx across cell membranes, with a stronger effect on vascular smooth muscle cells. This causes vasodilation, reducing peripheral vascular resistance, and consequently, lowering blood pressure.

Therapeutic Indications: Exforge 10/160 tablets are used to treat hypertension, a common condition where the long-term force of blood against artery walls is elevated, potentially leading to health problems such as heart disease. Lowering blood pressure with this medication reduces the risk of fatal and non-fatal cardiovascular events, including strokes and myocardial infarctions.

Method of Administration: Exforge 10/160 tablets should be taken exactly as prescribed by the doctor or pharmacist. The tablets are to be swallowed whole with a glass of water and can be taken with or without food. It is essential to take the daily dose at approximately the same time each day. Breaking the tablet in half should be avoided. If you accidentally take more than the recommended dose, seek medical attention promptly. If you forget to take a dose, take it as soon as you remember, but avoid taking a double dose to compensate for the missed one.

Undesirable Side Effects: Some of the potential side effects of Exforge 10/160 tablets include edema (swelling), vertigo, nasopharyngitis, upper respiratory tract infection, and dizziness.

Pregnancy and Breastfeeding Precautions: If you are pregnant, breastfeeding, think you may be pregnant, or planning to have a baby, consult your doctor or pharmacist before taking this medicine.

Non-Pharmacological Treatments and Advice to Reduce Blood Pressure: In addition to medication, non-pharmacological approaches to lower blood pressure include:

  • Losing weight and watching your waistline
  • Regular exercise
  • Eating a healthy diet
  • Reducing sodium intake
  • Quitting smoking
  • Limiting caffeine consumption
  • Managing stress
  • Monitoring blood pressure at home with appropriate devices
  • Regularly visiting your doctor for check-ups

Warnings and Special Precautions: Certain precautions should be taken while using Exforge 10/160 tablets. These include ensuring proper volume status before initiation, monitoring renal function and potassium levels in susceptible patients, and avoiding co-administration with specific medications like simvastatin and aliskiren. It is essential to discuss any potential interactions or risks with your healthcare provider.

Storage Conditions: Store Exforge 10/160 tablets below 25°C, avoiding refrigeration. Keep the medicine out of the sight and reach of children, and store it in the original package to protect it from moisture. Do not use the medicine after the expiry date mentioned on the box/blisters/label.

Blood Pressure Ranges: Normal blood pressure is indicated by numbers less than 120/80 mm Hg. Elevated blood pressure falls between 120-129 systolic and less than 80 mm Hg diastolic. Hypertension Stage 1 ranges from 130-139 systolic or 80-89 mm Hg diastolic, while Hypertension Stage 2 is at 140/90 mm Hg or higher. A hypertensive crisis, where immediate medical attention is required, occurs when blood pressure readings suddenly exceed 180/120 mm Hg.

For More Information About Valsartan & Amlodipine: For additional information, you can ask your physician or pharmacist or visit websites like the SFDA, Medscape, or for information about Valsartan & Amlodipine.


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